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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
11.5 DPC

18 matching records from 18 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dct  dopachrome tautomerase   (Synonyms: TRP2, TRP-2, tyrosinase-related protein-2, Tyrp2, Tyrp-2)
Results  Reference
1*J:78163 Baxter LL, Pavan WJ, The oculocutaneous albinism type IV gene Matp is a new marker of pigment cell precursors during mouse embryonic development. Mech Dev. 2002 Aug;116(1-2):209-12
1*J:86959 Baxter LL, Pavan WJ, Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Gene Expr Patterns. 2003 Dec;3(6):703-7
1J:160209 Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ, NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res. 2009 Dec;22(6):773-84
1*J:105843 Hakami RM, Hou L, Baxter LL, Loftus SK, Southard-Smith EM, Incao A, Cheng J, Pavan WJ, Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage. Mech Dev. 2006 Feb;123(2):124-34
1J:44094 Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S, Wnt signalling required for expansion of neural crest and CNS progenitors. Nature. 1997 Oct 30;389(6654):966-70
1J:101313 Lanning JL, Wallace JS, Zhang D, Diwakar G, Jiao Z, Hornyak TJ, Altered melanocyte differentiation and retinal pigmented epithelium transdifferentiation induced by Mash1 expression in pigment cell precursors. J Invest Dermatol. 2005 Oct;125(4):805-17
1*J:84057 Lee HO, Levorse JM, Shin MK, The endothelin receptor-B is required for the migration of neural crest-derived melanocyte and enteric neuron precursors. Dev Biol. 2003 Jul 1;259(1):162-75
1*J:157352 Loftus SK, Baxter LL, Buac K, Watkins-Chow DE, Larson DM, Pavan WJ, Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res. 2009 Oct;22(5):611-22
1*J:75774 Loftus SK, Larson DM, Baxter LL, Antonellis A, Chen Y, Wu X, Jiang Y, Bittner M, Hammer JA 3rd, Pavan WJ, Mutation of melanosome protein RAB38 in chocolate mice. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4471-6
1*J:71587 Potterf SB, Mollaaghababa R, Hou L, Southard-Smith EM, Hornyak TJ, Arnheiter H, Pavan WJ, Analysis of sox10 function in neural crest-derived melanocyte development: sox10-dependent transcriptional control of dopachrome tautomerase. Dev Biol. 2001 Sep 15;237(2):245-57
1*J:84755 Rao C, Foernzler D, Loftus SK, Liu S, McPherson JD, Jungers KA, Apte SS, Pavan WJ, Beier DR, A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation. Development. 2003 Oct;130(19):4665-72
1J:242073 Seberg HE, Van Otterloo E, Loftus SK, Liu H, Bonde G, Sompallae R, Gildea DE, Santana JF, Manak JR, Pavan WJ, Williams T, Cornell RA, TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PLoS Genet. 2017 Mar;13(3):e1006636
1*J:45117 Southard-Smith EM, Kos L, Pavan WJ, Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet. 1998 Jan;18(1):60-4
1J:169665 Stottmann RW, Klingensmith J, Bone morphogenetic protein signaling is required in the dorsal neural folds before neurulation for the induction of spinal neural crest cells and dorsal neurons. Dev Dyn. 2011 Apr;240(4):755-65
1*J:69377 Wehrle-Haller B, Meller M, Weston JA, Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival. Dev Biol. 2001 Apr 15;232(2):471-83
1*J:34586 Wehrle-Haller B, Morrison-Graham K, Weston JA, Ectopic c-kit expression affects the fate of melanocyte precursors in Patch mutant embryos. Dev Biol. 1996 Aug 1;177(2):463-74
1*J:40215 Wehrle-Haller B, Weston JA, Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway. Development. 1995 Mar;121(3):731-42
1*J:55577 Wehrle-Haller B, Weston JA, Altered cell-surface targeting of stem cell factor causes loss of melanocyte precursors in Steel17H mutant mice. Dev Biol. 1999 Jun 1;210(1):71-86

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory